Anti-Double Stranded DNA Mouse Monoclonal Antibody (CF488A) [clone: DSD/958]

Supplier: Biotium

BNC880958-100 BNC880958-500
75925-316EA 205.77 USD
75925-316 75925-318
Anti-Double Stranded DNA Mouse Monoclonal Antibody (CF488A) [clone: DSD/958]
Antibodies
This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Deoxyribonucleic acid (DNA) is a nucleic acid that stores long-term information regarding the development and function of all known living organisms. DNA consists of two long nucleotide polymers, which are composed of four bases, namely adenine, thymine, guanine and cytosine, all of which are flanked by a phosphate-deoxyribose backbone. Normally, DNA exists as a double-stranded (ds) molecule that forms in the shape of a double helix, allowing the bases and the backbone of the two strands to interact, thus forming a polynucleotide. When the double helix is unwound (either by enzymes or heat), DNA exists as a single-stranded (ss) molecule that is less stable than the double helix, but is necessary for protein access to DNA bases. Double stranded DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: Double Stranded DNA
Clonality: Monoclonal
Clone: Clone DSD/958
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG3 kappa
Reactivity: Human
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