Anti-UACA Mouse Monoclonal Antibody (CF594) [clone: AE-5]

Supplier: Biotium

BNC940956-100 BNC940956-500

75978-796EA 205.77 USD

75978-796 75978-798

Anti-UACA Mouse Monoclonal Antibody (CF594) [clone: AE-5]

Antibodies

UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: UACA
Clonality: Monoclonal
Clone: Clone AE-5
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Mouse

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