Anti-CD46 Mouse Monoclonal Antibody (CF568) [clone: 197-2B1]

Supplier: Biotium

BNC680931-100 BNC680931-500
75913-686EA 205.77 USD
75913-686 75913-688
Anti-CD46 Mouse Monoclonal Antibody (CF568) [clone: 197-2B1]
Antibodies
This antibody recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria. This MAb can be applied to test complement activation in pseudo-allergic reactions to acetylsalicylic acid and to test for measles virus infection of cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: CD46
Clonality: Monoclonal
Clone: Clone 197-2B1
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human
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