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Anti-NGFR Mouse Monoclonal Antibody (Biotin) [clone: NGFR5]

Supplier: Biotium

BNCB0890-100 BNCB0890-500

75965-992EA 205.77 USD

75965-992 75968-578

Anti-NGFR Mouse Monoclonal Antibody (Biotin) [clone: NGFR5]

Antibodies

This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.

Type: Primary
Antigen: NGFR
Clonality: Monoclonal
Clone: NGFR5
Conjugation: Biotin
Epitope:
Host: Mouse
Reactivity: Baboon, Cat, Ferret, Human, Monkey, Rabbit
Isotype: IgG1, kappa

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