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Anti-INS Mouse Monoclonal Antibody (CF640R) [clone: IRDN/794]

Supplier: Biotium

BNC400794-100 BNC400794-500

75954-920EA 205.77 USD

75954-920 75954-922

Anti-INS Mouse Monoclonal Antibody (CF640R) [clone: IRDN/794]

Antibodies

This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Type: Primary
Antigen: INS
Clonality: Monoclonal
Clone: IRDN/794
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Cow, Human, Mouse, Pig, Rat

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