Anti-SILV Mouse Monoclonal Antibody (CF568) [clone: PMEL/783]

Supplier: Biotium

BNC680783-100 BNC680783-500
75971-020EA 205.77 USD
75971-020 75971-022
Anti-SILV Mouse Monoclonal Antibody (CF568) [clone: PMEL/783]
Antibodies
Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: SILV
Clonality: Monoclonal
Clone: Clone PMEL/783
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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