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Anti-IGKC Mouse Monoclonal Antibody (CF647) [clone: HP6053 L1C1]

Supplier: Biotium

BNC470755-100 BNC470755-500

75955-496EA 205.77 USD

75955-496 75955-498

Anti-IGKC Mouse Monoclonal Antibody (CF647) [clone: HP6053 L1C1]

Antibodies

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: IGKC
Clonality: Monoclonal
Clone: Clone HP6053 L1C1
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human

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