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Anti-KDR Mouse Monoclonal Antibody (CF488A) [clone: Clone KDR721]

Supplier: Biotium

BNC880721-100 BNC880721-500

75981-078EA 205.77 USD

75981-078 75981-080

Anti-KDR Mouse Monoclonal Antibody (CF488A) [clone: Clone KDR721]

Antibodies

CD309, also known as VEGFR2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGFR2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: KDR
Clonality: Monoclonal
Clone: Clone KDR721
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human

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