Anti-KRT8 & KRT18 Mouse Monoclonal Antibody (CF488A) [clone: K8.8 DC10]

Supplier: Biotium

BNC880691-100 BNC880691-500
75920-878EA 205.77 USD
75920-878 75920-880
Anti-KRT8 & KRT18 Mouse Monoclonal Antibody (CF488A) [clone: K8.8 DC10]
Antibodies
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: KRT8 & KRT18
Clonality: Monoclonal
Clone: Clone K8.8 DC10
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human
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