Anti-VWF Mouse Monoclonal Antibody (CF488A) [clone: 3E2D10 VWF635]

Supplier: Biotium

BNC880646-100 BNC880646-500
75979-128EA 205.77 USD
75979-128 75979-130
Anti-VWF Mouse Monoclonal Antibody (CF488A) [clone: 3E2D10 VWF635]
Antibodies
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: VWF
Clonality: Monoclonal
Clone: Clone 3E2D10 VWF635
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human
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