Anti-PTPRC Mouse Monoclonal Antibody (CF568) [clone: PD7/26]

Supplier: Biotium

BNC680472-100 BNC680472-500
75913-274EA 205.77 USD
75913-274 75913-276
Anti-PTPRC Mouse Monoclonal Antibody (CF568) [clone: PD7/26]
Antibodies
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: Clone PD7/26
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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