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Anti-IL2RA Mouse Monoclonal Antibody (Biotin) [clone: 143-13]

Supplier: Biotium

BNCB0297-100 BNCB0297-500

75891-150EA 205.77 USD

75891-150 75891-152

Anti-IL2RA Mouse Monoclonal Antibody (Biotin) [clone: 143-13]

Antibodies

This antibody recognizes a protein of 55 kDa, identified as CD25 (Workshop IV; Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R beta chain, p75) and CD132 (common gamma chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb This antibody recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.

Type: Primary
Antigen: IL2RA
Clonality: Monoclonal
Clone: Clone 143-13
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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