Anti-CD70 Mouse Monoclonal Antibody [clone: BU69]

Supplier: Biotium

BNUB0187-100 BNUB0187-500
75918-856EA 240.92 USD
75918-856 75918-858
Anti-CD70 Mouse Monoclonal Antibody [clone: BU69]
Antibodies
This antibody recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown toinhibit T cell proliferation induced by dendritic cells.

Type: Primary
Antigen: CD70
Clonality: Monoclonal
Clone: Clone BU69
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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