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Anti-FN1 Mouse Monoclonal Antibody (CF640R) [clone: TV-1]

Supplier: Biotium

BNC400029-100 BNC400029-500

75927-064EA 205.77 USD

75927-064 75927-066

Anti-FN1 Mouse Monoclonal Antibody (CF640R) [clone: TV-1]

Antibodies

Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Type: Primary
Antigen: FN1
Clonality: Monoclonal
Clone: Clone TV-1
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Mouse, Pig, Rat

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