MethElute™ Reagent

Supplier: Thermo Scientific

TS-49300 TS-49301
10066-366EA 303.43 USD
10066-366 10066-368
MethElute™ Reagent
Chromatography Sorbents GC Sorbents

MethElute™ Reagent (TMPAH) ideally suits for the quantitative methylation and detection of barbiturates, sedatives, xanthine bases, phenolic alkaloids, and phenytoin, giving a single quantitative peak for each substance.


  • Highly precise, with coefficient of variation of 5% or less
  • High sensitivity
  • Barbiturates detected down to 0.2 mg/dl
  • Accuracy is similar or better than the UV/TLC method


When the reagent is heated with drug-containing extracts, serum, or urine the drugs containing reactive amino, hydroxyl, and carboxyl functions will be methylated at the reactive sites. Accuracy comparable or better than the UV/TLC method (GC is superior to UV/TLC when phenobarbitol and phenytoin present).


Hazards: Flammable, toxic.


Standard components: Trimethylanilinium hydroxide in methanol
Standard concentration: 0.2 M


Precaución: For research use only. Not for use in diagnostic procedures.

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