D-(+)-Biotin ≥97.5%, white crystalline powder cell culture reagent
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Storage: +4 °C
D-Biotin is a growth factor present in small amounts in every living cell. It is involved in naturally occurring carboxylation reactions. It occurs mainly bound to proteins or polypeptides. It is more abundant in the liver, kidney, pancreas, yeast and milk. Biotin levels are higher in cancerous tumors than in normal tissues. It is inactivated by binding to avidin.
D-Biotin may be used to elute proteins from avidin/streptavidin resins. It is widely used for dietary supplements and fortified foods. It is also used for tablets and hard-shell capsule preparation due to its pharmaceutical properties.
Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide.
Soluble in water (22 mg/100 mL), ethanol (80 mg/100 mL), more soluble in hot water and in dilute alkalies; insoluble in other common organic solvents. Soluble in 2 M Ammonium hydroxide (50 mg/mL - clear, colorless solution), dimethylformamide (1.7 mg/mL).
- Cell Culture Reagent Grade
- Refractive Index: 90.5 ° (C=2, 0.1mol/L NaOH) (Lit.)
- Presentation: White Crystalline Powder
- Isoelectric Point (pl): 3.5 (lit.)
- Reaction (0.02% aq soln)- Very Slightly Acidic to Litmus
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Formula:
C₁₀H₁₆N₂O₃S Boiling Pt: 573.6 °C (760 mmHg) Melting Pt: 223…233 °C Density: 1.267 g/cm³ (lit.) Storage Temperature: Refrigerator |
MDL Number:
MFCD00005541 CAS Number: 58-85-5 |
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Specification Test Results
| Identity Test | Passes |
| Purity | ≥97.5% |
| FTIR | Conforms to Standard |
| Solubility (0.02% aq soln) | Clear Solution |
| Reaction (0.02% aq soln) | Very Slightly Acid to Litmus |
| Optical Rotation (c=2, 0.1 N NaOH) | +89 to +93° |
| Organic Volatile Impurities | Passes |
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