Cefsulodin sodium salt
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Synonyms:
Cefsulodin sodium, Sodium (6R,7R)-3-((4-carbamoylpyridin-1-ium-1-yl)methyl)-8-oxo-7-((R)-2-phenyl-2-sulphonatoacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, Sulcephalosporin
Cefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. It has no significant activity against other Gram-negative bacteria and very limited activity against Gram-positive bacteria and anaerobic bacteria.
Cefsulodin is a cephalosporin. Cephalosporins disrupt cell wall synthesis by inhibiting PBP crosslinking of peptidoglycan.
Cefuslodin is most commonly used in CIN (cefsulodin-Irgasan-novobiocin) agar to select for Yersinia microorganisms and microorganisms such as E. coli.
Cefsulodin is a substrate for rat Oatp1a4. It has been used to study multidrug resistance-associated protein 4 in efflux transport of prostaglandin E2 across the mouse blood-brain barrier.
Cefsulodin is used to study the effect of expression, binding, and inhibition of PBP1 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
Store at +4 °C
Formula:
C₂₂H₁₉N₄NaO₈S₂ MW: 554.524 g/mol |
MDL Number:
MFCD07793338 CAS Number: 52152-93-9 |
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Specification Test Results
Physical Appearance | White to pale yellow solid |
Solubility | Soluble in water (50mg/mL-clear, faintly yellow solution). |
Storage | Store at +4 °C |
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