Human CD275 (from CHO cells)

Supplier: AdipoGen Life Sciences
ANC-575-030
102513-370EA 750.46 USD
102513-370
Human CD275 (from CHO cells)
Proteins and Peptides
The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.
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