Proteinase K

Supplier: MilliporeSigma

71049-3 71049-4 71049-4
80509-756EA 162.46 USD
80509-756 80509-758 102969-030
Proteinase K
Enzymes

Proteinase K is a highly active 28,904-Da serine protease isolated from the fungus Tritirachium album.


The enzyme exhibits broad cleavage specificity on native and denatured proteins and is widely used in the purification of DNA and RNA. Its activity is increased in the presence of denaturants such as SDS (1%) and elevated temperature (50 to 60 °C). Working concentration is 50 to 100 µg/ml for protein removal and enzyme inactivation and upto 2 mg/ml for tissue treatment. It is a lyophilized powder.

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