AEBSF hydrochloride (4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride) ≥97% (by HPLC), Calbiochem®
Supplier: MilliporeSigma
Synonyms:
4-(2-Aminoethyl)benzenesulphonyl fluoride hydrochloride, AEBSF hydrochloride
Packaged under inert gas.
Specific, irreversible inhibitor of serine proteases.
Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). A β-secretase inhibitor that inhibits β-amyloid peptide (Aβ) production and enhances amyloid precursor protein (sAPPUα) secretion in several cell lines at millimolar concentrations. Use at the same molar concentrations (0.1 to 1.0 mM) as PMSF for most applications. Also available as a 50 mM solution in H₂O (Cat. No. 508436).
Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes.
Special Instructions: Following reconstitution, store in the refrigerator (4 °C). Aqueous stock solutions are stable for up to 2 months at 4 °C. Slight hydrolysis occurs at alkaline pH (8 to 9).
Formula:
C₈H₁₁ClFNO₂S MW: 239.69 g/mol Storage Temperature: Ambient |
MDL Number:
MFCD00132962 CAS Number: 30827-99-7 Merck Index: 14.4654 |
Specification Test Results
Synonyms | 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl |
CAS number | 30827-99-7 |
Form | White to off-white solid |
Hill Formula | C8H10FNO2S.HCl |
Chemical formula | C8H10FNO2S.HCl |
Primary Target | chymotrypsin |
Purity | >97% by HPLC |
Storage | 15°C to 30°C |
VERP | Packaged under inert gas |
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