Human Recombinant TIMP-1 (from E. coli)

Supplier: Peprotech

410-01-2UG 410-01-10UG 410-01-50UG 410-01-100UG 410-01-250UG 410-01-500UG 410-01-1MG
10781-078EA 132.81 USD
10781-078 10781-080 10781-082 10781-084 10781-086 10781-088 10781-090
Human Recombinant TIMP-1 (from E. coli)
Proteins and Peptides

TIMP-1 is an extracellular inhibitor of MMPs, including MMP-1, -2, -3, -7, -8, -9, -10, -11, -12, -13, and -16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors. Recombinant Human TIMP-1 is a 20.6 kDa protein containing 184 amino acid residues.


Información para pedidos: For research use only. Not for use in diagnostic or therapeutic procedures.

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SPECIFICATIONS

Protein/Peptide Name TIMP-1
Protein Synonyms Tissue Inhibitor of Metalloproteinases 1|Fibroblast collagenase inhibitor|Erythroid-potentiating activity
Protein/Peptide Type Recombinant
Protein Function Cytokines and Growth Factors
Species Human
Source E. coli
Conjugation Unconjugated
Gene ID 7076 P01033
Sequence CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI KMTKMYKGFQ ALGDAADIRF VYTPAMESVC GYFHRSHNRS EEFLIAGKLQ DGLLHITTCS FVAPWNSLSL AQRRGFTKTY TVGCEECTVF PCLSIPCKLQ SGTHCLWTDQ LLQGSEKGFQ SRHLACLPRE PGLCTWQSLR SQIA
Protease-free Y
Endotoxin Level Low
Endotoxin Content >0.1 ng/μg
Biological Activity Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity 0.95
Form Lyophilized
Formulation Formulation can vary. Please refer to product CoA for information.
Molecular Weight 20.6 kDa
Reconstitution Instructions Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage Conditions Store at –20 °C prior to reconstitution.
Shipping Temperature Ambient

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