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Human Recombinant PAF-AH (from HEK293 Cells)

Supplier: Peprotech

140-10-5UG 140-10-20UG 140-10-100UG 140-10-250UG 140-10-500UG 140-10-1MG

10779-432EA 132.81 USD

10779-432 10779-434 10779-436 10779-438 10779-440 10779-442

Human Recombinant PAF-AH (from HEK293 Cells)

Proteins and Peptides

Platelet Activating Factor (PAF) is a biologically active phospholipid, which exerts primarily proinflammatory activities by specifically signaling through G-protein-coupled receptors on platelets, neutrophils, and monocytes. Platelet Activating Factor Acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by specifically catalyzing hydrolysis of the “sn2” ester bond, resulting in the conversion of PAF to the biologically inactive lyso-PAF. PAF-AH can also interact with LDL particles to induce the hydrolysis of LDL-associated, oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids. Recombinant Human PAF-AH is a 420 amino acid glycoprotein which migrates with an apparent molecular mass of 47-55 kDa by SDS-PAGE analysis. Recombinan Human PAF-AH has a calculated, theoretical meolecular weight of 47.8 kDa.

Información para pedidos: For research use only. Not for use in diagnostic or therapeutic procedures.

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