Mouse Recombinant IL-4 (from E. coli)

Supplier: Peprotech

AF-214-14-5UG AF-214-14-20UG AF-214-14-50UG AF-214-14-100UG AF-214-14-250UG AF-214-14-500UG AF-214-14-1MG

10778-476EA 183.07 USD

10778-476 10778-478 10778-480 10778-482 10778-484 10778-486 10778-488

Mouse Recombinant IL-4 (from E. coli)

Proteins and Peptides

IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant Murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues.

Animal-free

Información para pedidos: For research use only. Not for use in diagnostic or therapeutic procedures.

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