Human Recombinant Epiregulin (from E. coli)

Supplier: Peprotech

100-04-5UG 100-04-25UG 100-04-100UG 100-04-250UG 100-04-500UG 100-04-1MG

10770-642EA 139.89 USD

10770-642 10770-644 10770-646 10770-648 10770-650 10770-652

Human Recombinant Epiregulin (from E. coli)

Proteins and Peptides

Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Recombinant Human Epiregulin is a 5.6 kDa monomeric protein, containing 50 amino residues, which corresponds to the mature secreted Epiregulin sequence.

Información para pedidos: For research use only. Not for use in diagnostic or therapeutic procedures.

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