Dexamethasone, white powder

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Danger

Synonyms: Dexamethasonum, 9-Fluor-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadien-3,20-dion

0219004025 0219004080
IC19004025EA 51.57 USD
IC19004025 IC19004080
Dexamethasone, white powder
Dexamethasone

Dexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin).


It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein. Dexamethasone has been observed to induce apoptosis in human thymocytes and eosinophils but to inhibit apoptosis in neutrophils.


Dexamethasone is a glucocorticoid anti-inflammatory agent. It regulates T cell survival, growth, and differentiation. It also inhibits the induction of nitric oxide synthase.


Slightly soluble in water (10 mg/100 mL), ethanol (1 mg/mL), chloroform; sparingly soluble in acetone, alcohol, dioxane, and methanol; very slightly soluble in ether

Formula: C₂₂H₂₉FO₅
MW: 392.47 g/mol
Melting Pt: 262…264 °C (lit.)
MDL Number: MFCD00064136
CAS Number: 50-02-2
EINECS: 200-003-9
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Specification Test Results

Identity Test Passes
FTIR Conforms to Standard C
Loss on Drying ≤5.0%
Optical Rotation +72 ° to +80 ° (c=1, dioxane)

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