Fosfomycin disodium salt
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Synonyms:
Disodium (1R,2S)-1,2-Epoxypropylphosphonate, Phosphomycin Disodium Salt, (1R,2S)-1,2-Epoxypropylphosphonic Acid Disodium Salt
Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. Phosphomycin concentrates in kidney and bladder, reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents.
- White powder
Phosphomycin disodium salt is used to treat uncomplicated urinary tract infections and to reduce nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents
Phosphomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.
It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine.
Soluble in water (50 mg/mL- clear, colorless solution) and 1 M HCl (50 mg/mL)
Formula:
C₃H₅Na₂O₄P MW: 182.02 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD00056853 CAS Number: 26016-99-9 |
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