Cytochalasin D (from Zygosporium mansoni), white powder

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Danger

Synonyms: 7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-triene-1,17-dione 21(R)-acetate

0215077101 0215077105 0215077110
IC15077101EA 209.16 USD
IC15077101 IC15077105 76102-692
Cytochalasin D (from Zygosporium mansoni), white powder
Cytochalasin D

Cytochalasin D is a cell permeable fungal toxin that binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits. This compound causes the disruption of actin filaments and inhibition of actin polymerization.
Cytochalasin D possesses antibiotic and antitumor activity. It also impairs maintenance of long term potentiation (LTP) of actin filaments. It is implicated in promoting conditions favorable for depolymerizing actin.
Disrupts actin microfilaments and activates the p53-dependent pathways causing arrest of the cell cycle at the G1-S transition. Inhibits smooth muscle contraction. Inhibits insulin-stimulated, but not basal, transport of glucose.


  • Presentation: White Powder
  • Soluble in chloroform (10 mg/mL - clear, colorless solution), CH2Cl2 (10 mg/ mL - clear colorless solution), DMSO and ethanol.
  • Storage temperature: Store at -20 °C, protect from light. Store Dessicated.

Formula: C₃₀H₃₇NO₆
MW: 507.63 g/mol
Melting Pt: 193…195 °C (lit.)
Storage Temperature: Freezer
MDL Number: MFCD00077706
CAS Number: 22144-77-0
UN: 1544
ADR: 6.1,II
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Specification Test Results

Identity Test Passes
Source Zygosporium mansoni

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