Squalene ≥98%, clear, colorless liquid

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
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0210294880 0210294890 0210294891 0210294810
IC10294880EA 163.37 USD
IC10294880 IC10294890 IC10294891 76102-770
Squalene ≥98%, clear, colorless liquid
Squalene

Squalene, an isoprenoid compound structurally similar to beta-carotene, is an intermediate metabolite in the synthesis of cholesterol.


Squalene is not very susceptible to peroxidation and appears to function in the skin as a quencher of singlet oxygen, protecting human skin surface from lipid peroxidation due to exposure to UV and other sources of ionizing radiation. Supplementation of squalene to mice has resulted in marked increases in cellular and non-specific immune functions in a dose-dependent manner. Squalene may also act as a "sink" for highly lipophilic xenobiotics. Since it is a nonpolar substance, it has a higher affinity for un-ionized drugs.


Squalene is the biochemical precursor to the whole family of steroids. Supplementation of the diet with squalene can reduce cholesterol and triglyceride levels. In humans, squalene might be a useful addition to potentiate the effects of some cholesterol-lowering drugs. The primary therapeutic use of squalene currently is as an adjunctive therapy in a variety of cancers.
Biosynthetic precursor to all steroids. Cytoprotective to normal cells exposed to carcinogens and antitumor agents.


Squalene, an isoprenoid compound structurally similar to beta-carotene, is an intermediate metabolite in the synthesis of cholesterol. Squalene is not very susceptible to peroxidation and appears to function in the skin as a quencher of singlet oxygen, protecting human skin surface from lipid peroxidation due to exposure to UV and other sources of ionizing radiation. Supplementation of squalene to mice has resulted in marked increases in cellular and non-specific immune functions in a dose-dependent manner. Squalene may also act as a "sink" for highly lipophilic xenobiotics. Since it is a nonpolar substance, it has a higher affinity for un-ionized drugs.


Precaución: Research Use Only (RUO).

Formula: C₃₀H₅₀
Boiling Pt: 285 °C (25 mmHg) (lit.)
Melting Pt: –75 °C (lit.)
Density: 0.858 g/mL (25 °C) (lit.)
Storage Temperature: Ambient
MDL Number: MFCD00008912
CAS Number: 111-02-4
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Specification Test Results

Identity Test Passes
Purity ≥98%
FTIR Conforms to Standard

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