Squalene ≥98%, clear, colorless liquid
Supplier: MP BIOMEDICALS (FKA ICN BIOMED
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Danger
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Squalene, an isoprenoid compound structurally similar to beta-carotene, is an intermediate metabolite in the synthesis of cholesterol.
Squalene is not very susceptible to peroxidation and appears to function in the skin as a quencher of singlet oxygen, protecting human skin surface from lipid peroxidation due to exposure to UV and other sources of ionizing radiation. Supplementation of squalene to mice has resulted in marked increases in cellular and non-specific immune functions in a dose-dependent manner. Squalene may also act as a "sink" for highly lipophilic xenobiotics. Since it is a nonpolar substance, it has a higher affinity for un-ionized drugs.
Squalene is the biochemical precursor to the whole family of steroids. Supplementation of the diet with squalene can reduce cholesterol and triglyceride levels. In humans, squalene might be a useful addition to potentiate the effects of some cholesterol-lowering drugs. The primary therapeutic use of squalene currently is as an adjunctive therapy in a variety of cancers.
Biosynthetic precursor to all steroids. Cytoprotective to normal cells exposed to carcinogens and antitumor agents.
Squalene, an isoprenoid compound structurally similar to beta-carotene, is an intermediate metabolite in the synthesis of cholesterol. Squalene is not very susceptible to peroxidation and appears to function in the skin as a quencher of singlet oxygen, protecting human skin surface from lipid peroxidation due to exposure to UV and other sources of ionizing radiation. Supplementation of squalene to mice has resulted in marked increases in cellular and non-specific immune functions in a dose-dependent manner. Squalene may also act as a "sink" for highly lipophilic xenobiotics. Since it is a nonpolar substance, it has a higher affinity for un-ionized drugs.
Precaución: Research Use Only (RUO).
Formula:
C₃₀H₅₀ Boiling Pt: 285 °C (25 mmHg) (lit.) Melting Pt: –75 °C (lit.) Density: 0.858 g/mL (25 °C) (lit.) Storage Temperature: Ambient |
MDL Number:
MFCD00008912 CAS Number: 111-02-4 |
Specification Test Results
Identity Test | Passes |
Purity | ≥98% |
FTIR | Conforms to Standard |
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