17-AAG 99%
Supplier: Thermo Scientific Chemicals
Synonyms:
17-(Allylamino)-17-demethoxygeldanamycin, Tanespimycin, (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2
- Possesses anti-tumor activity
17-AAG also induces apoptosis alond with its anti-tumor effects.
Formula:
C₃₁H₄₃N₃O₈ MW: 585.7 g/mol Melting Pt: 207…209 °C Flash Pt: >110 °C(230 °F) Storage Temperature: Refrigerator |
MDL Number:
MFCD04973892 CAS Number: 75747-14-7 |
Specification Test Results
Assay | 99% |
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