Cp 31398 Dihydrochloride (synthetic) ≥98% (by TLC)

Supplier: Enzo Life Sciences

Synonyms: N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride

BML-GR360-0010 BML-GR360-0050

89159-000EA 163.5 USD

89159-000 89160-000

Cp 31398 Dihydrochloride (synthetic) ≥98% (by TLC)

Cp 31398 Dihydrochloride

CP-31398 restores mutant p53 tumor suppressor function in vitro without affecting p53 homologs p63 and p73, and in vivo inhibiting UVB-induced skin carcinogenesis in mice. Stabilization of p53 inhibits ubiquitination without altering phosphorylation at Ser12 or Ser20 or MDM2 binding. Administration of this or similar compounds has the potential to enhance cytotoxic chemotherapy.

p53 activator

Yellow solid.

Soluble in water (25mg/ml) or DMSO (5mg/ml).

Formula: C₂₂H₂₈Cl₂N₄O
MW: 435.393 g/mol
Storage Temperature: Freezer

MDL Number: MFCD11519956
CAS Number: 259199-65-0

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