SMER28 (synthetic) ≥98% (by TLC)

Supplier: Enzo Life Sciences

Corrosive Warning

Irritant Warning

Danger

Synonyms: N-Allyl-6-bromoquinazolin-4-amine

BML-EI397-0005 BML-EI397-0025

89158-274EA 120.99 USD

89158-274 89158-276

SMER28 (synthetic) ≥98% (by TLC)

SMER28

Small molecule inducer of autophagy important for neurodegenerative disease research.

Formulation: Off-white solid.

Chemical inducer of autophagy which acts via an mTOR-independent mechanism. It increased autophagosome synthesis and enhanced the clearance of model autophagy substrates such as A53T alpha-synuclein and mutant huntingtin fragments. It reduced Aβ peptide and AAP-CTF levels in an alzheimers model and attenuated mutant huntingtin-fragment toxicity in Huntington's disease models, suggesting therapeutic potential.

Soluble in DMSO (8 mg/mL) or 100% ethanol (2 mg/mL).

Formula: C₁₁H₁₀BrN₃
MW: 264.126 g/mol
Storage Temperature: Freezer

MDL Number: MFCD02166825
CAS Number: 307538-42-7

https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=19178c6ec4a62c3daad860922cad6919572a2c12&vid=3403fed074ec12a0d9f0e73b459d1ac648359048&prid=web&clid=SAPDAM

Specification Test Results

Source	Synthetic
Purity (TLC)	≥98%

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