SC-514 ≥98% (by TLC)

Supplier: Enzo Life Sciences

Synonyms: 4-amino-[2,3'-bithiophene]-5-carboxamide, IKK-2 Inhibitor, SC-514

BML-EI343-0010 BML-EI343-0050
89158-128EA 124.26 USD
89158-128 89158-130
SC-514 ≥98% (by TLC)
SC-514

IKK inhibitor


Selective, reversible and ATP-competitive inhibitor of IKK2 (IC50=11.2µM). Does not inhibit other IKK isoforms or other serine/threonine or tyrosine kinases. Inhibits transcription of NF-κB dependent genes in IL-1β-induced rheumatoid arthritis-derived synovial fibroblasts in a dose-dependent fashion.

Formula: C₉H₈N₂OS₂
MW: 224.3 g/mol
MDL Number: MFCD00206459
CAS Number: 354812-17-2
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