Bisindolylmaleimide I ≥98% (by TLC)

Supplier: Enzo Life Sciences

Bisindolylmaleimide I ≥98% (by TLC)

Bisindolylmaleimide I ≥98% (by TLC)

Synonyms: 3-(1-(3-(Dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione, 3-[1-[3-(Dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione, GF 109203X

BML-EI246-0001 BML-EI246-0005

89157-860EA 107.91 USD

89157-860 76002-076

Bisindolylmaleimide I ≥98% (by TLC)

Bisindolylmaleimide I

Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.

PKC inhibitor

Red solid.

Soluble in dimethyl formamide or DMSO (10mg/ml, warm to 40°C and vortex well).

Formula: C₂₅H₂₄N₄O₂
MW: 412.48 g/mol
Storage Temperature: Freezer

MDL Number: MFCD00236428
CAS Number: 133052-90-1

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