SKF-96365 hydrochloride ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Synonyms: 1-(2-(4-Methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole hydrochloride, 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]-1H-imidazole hydrochloride, SKF-96365

BML-CA230-0005 BML-CA230-0025

89156-792EA 163.5 USD

89156-792 89156-794

SKF-96365 hydrochloride ≥98% (by HPLC)

SKF-96365 hydrochloride

A novel, selective inhibitor of receptor-mediated calcium entry. It inhibits receptor-mediated calcium entry in stimulated platelets (IC50=8-12µM) neutrophils and endothelial cells at concentrations which do not affect internal Ca2+ release. Note, in some cells SK&F 96365 can activate a novel Ca2+ entry pathway. Blocks TRPC3 and TRPC6 activation. Inhibits the histamine-induced formation of nitric oxide in human endothelial cells.

TRP channel blocker

White solid.

Soluble in water (30mg/ml).

Formula: C₂₂H₂₆N₂O₃·HCl
MW: 402.9 g/mol
Melting Pt: 117…119 °C
Storage Temperature: Ambient

MDL Number: MFCD00236407
CAS Number: 130495-35-1

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