IM-54 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Synonyms: 1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione

430-137-M001 430-137-M005
89151-204EA 49.05 USD
89151-204 89151-206 89151-208
IM-54 ≥98% (by HPLC)
IM-54

Cell permeable inhibitor of necrosis


Selectively blocks oxidative stress-induced necrotic cell death (~3 µm IM-54 prevented ~50% cell death in HL60 cells exposed to 100 µm H2O2). Does not protect against etoposide-induced apoptosis or display antioxidant properties. Does not affect S6K1 and PKC kinase activities at concentrations of 50 µm.

Formula: C₁₉H₂₃N₃O₂
MW: 325.40 g/mol
MDL Number: MFCD18382109
CAS Number: 861891-50-1
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