HA14-1 ≥95% (by 1H-NMR)

Supplier: Enzo Life Sciences

Synonyms: Ethyl-2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate, rel-(R)-Ethyl 2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative)

430-101-M005 430-101-M025
89151-112EA 78.48 USD
89151-112 89151-114
HA14-1 ≥95% (by 1H-NMR)
HA14-1

Bcl-2 ligand.


  • Formulation: Off-white to light yellow powder.


Cell permeable, low molecular weight Bcl-2 ligand. Antagonizes the function of Bcl-2 and induces apoptosis. In HL-60 cells, HA4-1 (50µM and 4h incubation) induced apoptosis of more than 90% of the cells. Apoptosis is blocked by ZVAD-FM. IC50 = ~9µM for competition with Flu-BakBH3 binding to Bcl-2.


Soluble in DMSO (25 mg/mL, dimethyl formamide or halogenated solvents; also soluble in 100% ethanol (25 mg, 7 mL hot).

Formula: C₁₇H₁₇BrN₂O₅
MW: 409.24 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00218213
CAS Number: 65673-63-4
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Specification Test Results

Purity (¹H-NMR) ≥95%
Identity Identity determined by IR, ¹H-NMR
Appearance Off-white to light yellow powder

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