cis-Platin ≥98%
Supplier: Enzo Life Sciences
Synonyms:
Platinol, cis-Diaminodichloroplatinum(II), cis-Diamminedichloroplatinum (II), cis-Dichlorodiammine platinum(II), Cisplatin, cis-Diamineplatinum(II) dichloride
Antitumor agent
- Formulation: Off-white to orange powder.
- Endotoxin-content: ≤1.0EU/mg
A potent platinum-based antineoplastic drug. Its mode of action invovles formation of inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. Platinated DNA adducts also enhance poisoning of DNA topoisomerase I. Cisplatin synergizes with a variety of anticancer agents. Tumor cells rapidly develop resistance to cisplatin and numerous agents are available to block or reverse resistance.
Formula:
H₆Cl₂N₂Pt MW: 300.05 g/mol |
MDL Number:
MFCD00011623 CAS Number: 15663-27-1 UN: 3288 ADR: 6.1,II |
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