Thiostrepton

Supplier: Enzo Life Sciences

Synonyms: N-[(7R,8S)-2-Carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-isoleucyl-L-alanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexadecahydro-11,28-bis[(1R)-1-hydroxyethyl]-9,12,19,26-tetraoxo-17H,26H-8,5:18,15:25,22:32,29-tetranitrilo-5H,15H-pyrido[3,2-m][1,11,17,24,4,7,20,27]tetrathiatetraazacyclotriacontin-2-yl]-4-thiazolecarbonyl-2,3-didehydroalanyl-2,3-didehydro-alaninamide,(1→528)-lactone

380-261-G001 380-261-G005

89150-282EA 163.5 USD

89150-282 89150-284

Thiostrepton

Thiostrepton

Elongation factor G inhibitor

Thiazole-containing peptide antibiotic. Inhibits protein synthesis by preventing binding of GTP to the 50S ribosomal subunit. Inhibits binding of elongation factor G (EF-G) and the dissociation of EF-G from the ribosome.

Isolated from Streptomyces azureus.

Formula: C₇₂H₈₅N₁₉O₁₈S₅
MW: 1664.887 g/mol

MDL Number: MFCD00135828
CAS Number: 1393-48-2

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