Microcystin-YR

Supplier: Enzo Life Sciences

350-044-C025 350-044-C100
89148-976EA 240.89 USD
89148-976 89148-978
Microcystin-YR
Proteins and Peptides

Inhibitor of PP1 and PP2A


Analog of microcystin-LR (Prod. No. ALX-350-012) with Tyr substituted in place of Leu. As for all microcystins the conjugated double bonds in the ADDA moiety cause a characteristic absorption maximum at 238nm. The Tyr residue in position 2 of microcystin-YR confers an absorption maximum at 232nm. Potent inhibitor of eukaryotic protein phosphatases 1 and 2A. Useful as a reference compound in environmental analysis. The hydroxyl group of the Tyr residue may prove useful for linking microcystin-YR via conjugation to other chemicals. Inhibits the synthesis of proteases such as cathepsin D and L, and arginine aminopeptidase.


Isolated from Microcystis aeruginosa.

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