1-Azakenpaullone ≥95% (by NMR)

Supplier: Enzo Life Sciences

Synonyms: 9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one

270-430-M001 270-430-M005
89147-882EA 150.42 USD
89147-882 89147-884
1-Azakenpaullone ≥95% (by NMR)
1-Azakenpaullone

GSK-3beta inhibitor


Analog of kenpaullone (Prod. No. BML-EI310) acting as a potent and ATP-competitive inhibitor of GSK-3beta (IC50=18nM). Displays ~100-200 fold greater selectivity on GSK-3beta than over CDK1/cyclin B and CDK5/p25 (IC50=2.0µM and 4.2µM, respectively).

Formula: C₁₅H₁₀BrN₃O
MW: 328.2 g/mol
MDL Number: MFCD09037522
CAS Number: 676596-65-9
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