1-Azakenpaullone ≥95% (by NMR)
Supplier: Enzo Life Sciences
Synonyms:
9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one
270-430-M001
270-430-M005
89147-882EA
150.42
USD
89147-882
89147-884
1-Azakenpaullone ≥95% (by NMR)
1-Azakenpaullone
GSK-3beta inhibitor
Analog of kenpaullone (Prod. No. BML-EI310) acting as a potent and ATP-competitive inhibitor of GSK-3beta (IC50=18nM). Displays ~100-200 fold greater selectivity on GSK-3beta than over CDK1/cyclin B and CDK5/p25 (IC50=2.0µM and 4.2µM, respectively).
Formula:
C₁₅H₁₀BrN₃O MW: 328.2 g/mol |
MDL Number:
MFCD09037522 CAS Number: 676596-65-9 |
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