3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one

Supplier: BACHEM AMERICAS INC

Synonyms: Diethyl (4-oxobenzo[d][1,2,3]triazin-3(4H)-yl) phosphate, DEPBT, Diethyl 3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl Phosphate

4029249.0025 4029249.0100
Q-2565.0025BAEA 392.15 USD
Q-2565.0025BA Q-2565.0100BA
3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one
3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one

Sequence: 3-(Diethoxy-phosphoryloxy)-1,2,3-benzo[d]triazin-4(3H)-one


DEPBT, a crystalline phosphonium-type coupling reagent, mediates amide bond formation with a remarkable resistance to racemization. Thus, DEPBT is an excellent activation reagent for coupling the racemization-prone Fmoc-His(Trt)-OH. The use of DEPBT permitted the total synthesis of the antiviral peptide antibiotic feglymycin, which contains a high proportion of ring-substituted phenylglycines.

Formula: C₁₁H₁₄N₃O₅P
MW: 299.22 g/mol
Storage Temperature: Freezer
MDL Number: MFCD01236967
CAS Number: 165534-43-0

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