3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one
Supplier: BACHEM AMERICAS INC
Synonyms:
Diethyl (4-oxobenzo[d][1,2,3]triazin-3(4H)-yl) phosphate, DEPBT, Diethyl 3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl Phosphate
Sequence: 3-(Diethoxy-phosphoryloxy)-1,2,3-benzo[d]triazin-4(3H)-one
DEPBT, a crystalline phosphonium-type coupling reagent, mediates amide bond formation with a remarkable resistance to racemization. Thus, DEPBT is an excellent activation reagent for coupling the racemization-prone Fmoc-His(Trt)-OH. The use of DEPBT permitted the total synthesis of the antiviral peptide antibiotic feglymycin, which contains a high proportion of ring-substituted phenylglycines.
Formula:
C₁₁H₁₄N₃O₅P MW: 299.22 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD01236967 CAS Number: 165534-43-0 |
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