Dec-RVKR-CMK
Supplier: BACHEM AMERICAS INC
Sequence: Decanoyl-Arg-Val-Lys-Arg-chloromethylketone
Synonym(s): Furin Inhibitor I#Dec-RVKR-CMK#Furin Convertase Inhibitor (Chloromethylketone)
Dec-RVKR-CMK binds to the catalytic site of furin and therefore acts as a potent inhibitor of cleavage and fusion activity of viral glycoproteins, as well as virus replication. Furthermore it was demonstrated that this compound decreased the production of β-amyloid-induced active matrix metalloproteinase 2 in U87 cells. Apart from furin, N-1505 also inhibited the proprotein convertases PC7/LPC, PACE4, and PC6 (W.Garten, personal communication).
Formula:
C₃₄H₆₆ClN₁₁O₅ Storage Temperature: Freezer |
MDL Number:
MFCD18910843 CAS Number: 150113-99-8 |
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