Mca-Amyloid beta/A4 Protein Precursor₇₇₀ (667-676)-Lys(Dnp)-Arg-Arg amide Trifluoroacetate

Supplier: BACHEM AMERICAS INC

4033759.0001 4033759.0005
M-2460.0001BAEA 571.91 USD
M-2460.0001BA M-2460.0005BA
Mca-Amyloid beta/A4 Protein Precursor₇₇₀ (667-676)-Lys(Dnp)-Arg-Arg amide Trifluoroacetate
Proteins and Peptides

This fluorescent (FRET) peptide substrate contains the wild-type amyloid precursor protein (APP) β-secretase cleavage site. Mca-SEVKMDAEFRK(Dnp)RR- amide has been used for assaying β-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). The results suggested that TOP is a potential β-secretase candidate and is involved in the processing of APP in vivo. See also L-1905.

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