Ureidosuccinic acid
Supplier: BACHEM AMERICAS INC
Synonyms:
Carbamoyl-Asp-OH·magnesium salt/Carbamoyl-Asp-OH·dipotassium salt (1:1)
Sequence: Carbamoyl-Asp-OH · magnesium salt/Carbamoyl-Asp-OH · dipotassium salt (1:1)
Asp-NH₂ is also called isoasparagine, so our Asp-NH₂ derivatives are assembled in the "Isoasparagine" subfamily.
Substrate for the determination of E.coli dihydroorotase (EC 3.5.2.3.), which catalyzes the cyclization of carbamoyl-Asp-OH into L-5,6-dihydroorotate. This enzyme being in the biosynthetic pathway of pyrimidine nucleotides, is an important therapeutic target for the design of new antineoplastic agents. Its activity was assayed spectrophotometrically measuring the increase of absorbance at 230 nm (ε₂₃₀ = 1170 M⁻¹cm⁻¹, Km = 0.47 mM, kcat = 143 s⁻¹).
Formula:
C₅H₈N₂O₅ MW: 176.128 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD03613594 CAS Number: 13184-27-5 EINECS: 236-134-3 |
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