Ureidosuccinic acid

Supplier: BACHEM AMERICAS INC

Synonyms: Carbamoyl-Asp-OH·magnesium salt/Carbamoyl-Asp-OH·dipotassium salt (1:1)

4027537.0001 4027537.0005
M-2240.0001BAEA 114.5 USD
M-2240.0001BA M-2240.0005BA
Ureidosuccinic acid
Ureidosuccinic acid

Sequence: Carbamoyl-Asp-OH · magnesium salt/Carbamoyl-Asp-OH · dipotassium salt (1:1)


Asp-NH₂ is also called isoasparagine, so our Asp-NH₂ derivatives are assembled in the "Isoasparagine" subfamily.


Substrate for the determination of E.coli dihydroorotase (EC 3.5.2.3.), which catalyzes the cyclization of carbamoyl-Asp-OH into L-5,6-dihydroorotate. This enzyme being in the biosynthetic pathway of pyrimidine nucleotides, is an important therapeutic target for the design of new antineoplastic agents. Its activity was assayed spectrophotometrically measuring the increase of absorbance at 230 nm (ε₂₃₀ = 1170 M⁻¹cm⁻¹, Km = 0.47 mM, kcat = 143 s⁻¹).

Formula: C₅H₈N₂O₅
MW: 176.128 g/mol
Storage Temperature: Refrigerator
MDL Number: MFCD03613594
CAS Number: 13184-27-5
EINECS: 236-134-3

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