Boc-Arg-Val-Arg-Arg-AMC
Supplier: BACHEM AMERICAS INC
Synonyms:
N-Boc-Arg-Val-Arg-Arg-7-amino-4-methylcoumarin
4018735.0025
4018735.0100
I-1645.0025BAEA
429.44
USD
I-1645.0025BA
I-1645.0100BA
Boc-Arg-Val-Arg-Arg-AMC
Boc-Arg-Val-Arg-Arg-AMC
Sequence: Boc-Arg-Val-Arg-Arg-AMC
The fluorogenic substrate Boc-RVRR-AMC is efficiently cleaved by furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km approx. 4·10³ M⁻¹s⁻¹). As a calcium-dependent serine protease associated with Golgi membranes, furin is responsible for the secretory processing of precursor proteins at paired basic residues. Boc-RVRR-AMC is also cleaved by proprotein convertase 4. Stock solutions of Boc-RVRR-AMC are best prepared in DMSO.
Formula:
C₃₈H₆₂N₁₄O₈ Storage Temperature: Freezer |
MDL Number:
MFCD02259613 CAS Number: 136132-77-9 |
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