N-Cbz-glycyl-glycyl-L-arginine 7-amido-4-methylcoumarin hydrochloride

Supplier: BACHEM AMERICAS INC

Synonyms: Z-Gly-Gly-Arg-AMC·HCl

4002155.0025 4002155.0100

I-1140.0025BAEA 305.82 USD

I-1140.0025BA I-1140.0100BA

N-Cbz-glycyl-glycyl-L-arginine 7-amido-4-methylcoumarin hydrochloride

N-Cbz-glycyl-glycyl-L-arginine 7-amido-4-methylcoumarin hydrochloride

Sequence: Z-Gly-Gly-Arg-AMC · HCl

Thrombin substrates are often cleaved as well by trypsin and trypsin-like enzymes, e.g. I-1365, I-1560, J-1120, and L-1150.

Z-GGR-AMC has been used as substrate in a direct fluorometric assay of urokinase and tissue-type plasminogen activator as well as for assaying trypsin and thrombin. I-1140 is used as thrombin substrate in the calibrated automated thrombogram (CAT), an automated test developed by Hemker et al., for determining hyper- and hypocoagulability. Z-GGR-AMC can also be used for determining the tryptic activity of proteasomes.

Formula: C₂₈H₃₄ClN₇O₇
MW: 616.072 g/mol
Storage Temperature: Freezer

MDL Number: MFCD00039016
CAS Number: 102601-58-1

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