O-Phospho-L-tyrosine

Supplier: BACHEM AMERICAS INC

Synonyms: H-tyr(H2po3)-oh, H-Tyr(PO₃H₂)-OH, H-Tyr(H₂PO₃)-OH

4025464.0005 4025464.0025

F-4180.0005BAEA 347.48 USD

F-4180.0005BA F-4180.0025BA

O-Phospho-L-tyrosine

O-Phospho-L-tyrosine

Sequence: H-Tyr(PO₃H₂)-OH

Besides a large selection of tyrosine derivatives, Bachem offers derivatives of O-alkylated tyrosines, thyronine, phosphotyrosine and sulfotyrosine. Bachem additionally offers H-[¹⁵N]Tyr-OH, E-3245.
For stable phosphotyrosine mimics see the O-malonyltyrosine derivative B-2825 and the 4-phosphonophenylalanine derivatives B-3895 and A-4725.

L-Phosphotyrosine can be used in the detection and quantification of tyrosine phosphorylation in proteins and as starting material in the synthesis of fluorescent substrates for protein tyrosine phosphatase assays. Furthermore, it has been incorporated in cyclic hexapeptides for studying intramolecular quenching of tryptophan fluorescence. L-Phosphotyrosine inhibits cellular growth by activating protein tyrosine phosphatases (Mishra and Hamburger). The phosphorylated amino acid protects TP53 wild-type cells against ionizing radiation.

Formula: C₉H₁₂NO₆
MW: 261.17 g/mol
Storage Temperature: Freezer

MDL Number: MFCD00002603
CAS Number: 21820-51-9

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