L-Propargylglycine
Supplier: BACHEM AMERICAS INC
Synonyms:
H-Pra-OH, (S)-2-Aminopent-4-ynoic acid, (S)-alpha-Propargylglycine
Sequence: H-Pra-OH
Synonym(s): H-Propargyl-Gly-OH#(S)-2-Amino-4-pentynoic acid
Bachem also offers resin-bound propargylglycine, Fmoc-Pra-Wang resin (D-2820).
This unusual amino acid is produced by microorganisms, it has been detected in the poisonous mushroom Amanita abrupta. Propargylglycine is a prececursor for tritiated norleucine which may be introduced synthetically into peptides. For a review of the synthetic applications of aliphatic unsaturated α-amino acids see Kaiser et al. Pra has been used in click chemistry. Cyclization of Pra-containing peptides via triazole formation with a lateral azide group proceeds smoothly in the presence of CuBr.
Formula:
C₅H₇NO₂ MW: 113.116 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00077855 CAS Number: 23235-01-0 |
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