1-Benzyl-N-carbobenzoxy-L-glutamate
Supplier: BACHEM AMERICAS INC
Synonyms:
N-Cbz-L-glutamic Acid 1-Benzyl Ester, N-Benzyloxycarbonyl-L-glutamic acid 1-benzyl ester, Z-Glu-OBzl, 1-Benzyl N-Cbz-L-glutamate, N-Carbobenzoxy-L-glutamic Acid 1-Benzyl Ester
Sequence: Z-Glu-OBzl
The derivatives of Glu-NH₂ are assembled in the "Isoglutamine" subfamily.
Educt for the γ-modification of glutamic acid, e.g. for obtaining the 1- and 2-adamantyl ester, acid-labile γ-carboxyl protecting groups. Feichtinger et al. obtained δ,ω,ω'-protected arginine from Z-Glu-OBzl via reduction to the alcohol followed by guanidinylation under Mitsunobu conditions. Additionally, Z-Glu-OBzl has been used as highly effective acyl donor in enzymatic peptide synthesis.
Formula:
C₂₀H₂₁NO₆ MW: 371.39 g/mol Storage Temperature: Ambient |
MDL Number:
MFCD00077013 CAS Number: 3705-42-8 |
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