(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl)amino)butanoic acid

Supplier: BACHEM AMERICAS INC

Synonyms: Fmoc-Dab(ivDde)-OH

4066591.0001 4066591.0005
B-4065.0001BAEA 370.19 USD
B-4065.0001BA B-4065.0005BA
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl)amino)butanoic acid
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl)amino)butanoic acid

Sequence: Fmoc-Dab(ivDde)-OH


The ivDde group can be cleaved selectively with 2% hydrazine hydrate in DMF. It is more stable towards the repetitve piperidine treatment during Fmoc-SPPS than Dde. ivDde has been applied in de Visser's synthesis of the Dab-rich cyclopeptide antibiotic polymyxin B1 and analogs.

Formula: C₃₂H₃₈N₂O₆
MW: 546.664 g/mol
Storage Temperature: Refrigerator
MDL Number: MFCD01631660
CAS Number: 607366-21-2

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